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Can I take ibuprofen with letrozole? No interactions were found between ibuprofen and letrozole.This does not necessarily mean no interactions exist. Always consult your healthcare provider. Why do you gain weight from aromatase inhibitors? Your extra weight may hang around and increase after chemotherapy if you also take hormonal therapy (tamoxifen or an aromatase inhibitor). If your body shifts into menopause because of chemotherapy, there's a tendency to gain weight. With less estrogen in the body, LPL can pull fat into fat cells and store it there. How many years should I take letrozole? How long will I have to take it? This will depend on your individual circumstances, but letrozole is usually taken for five to ten years. Some people start taking letrozole after a few years of taking the hormone therapy drug tamoxifen.
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